EBOO Therapy
Cleaning the Bloodstream
with Ozone & Oxygen
Your blood touches every cell in your body. When the bloodstream is carrying a heavy load of pathogens, oxidative stress, or toxins, it shows up everywhere: fatigue, brain fog, immune dysfunction, chronic illness that won’t quite resolve. EBOO is a therapy that works directly on that bloodstream, using a controlled exposure to ozone and oxygen to support the body’s ability to clear what it’s carrying.
What is EBOO?
EBOO stands for Extracorporeal Blood Ozone Oxygenation. It’s a therapy in which a portion of your blood is gently circulated outside the body, exposed to medical-grade ozone and oxygen, and then returned to your circulation. The whole process happens in a closed, sterile circuit, and you remain comfortably in a treatment chair the entire time.
Ozone is a naturally occurring molecule made of three oxygen atoms. In medical use, it has been studied for decades as a tool for supporting immune function, reducing certain pathogens, and improving oxygen utilization at the cellular level. EBOO is one of the more advanced ways to deliver ozone therapy, because it treats a larger volume of blood than other ozone methods and exposes that blood to oxygen-rich ozone in a controlled, measurable way.
How EBOO Works
During a session, your blood is gently circulated through a closed, sterile circuit where it’s exposed to medical-grade ozone and oxygen, and then returned to you. Here’s what happens next.
Your antioxidant systems wake up. Controlled ozone exposure stimulates the body’s own antioxidant defense pathways in a measured way. Rather than overwhelming your system, it gives it a nudge to do the work it was designed to do, which can help reduce the longer-term oxidative burden many chronically ill patients carry.
Your blood carries oxygen better. The oxygen component of the therapy improves how efficiently your blood delivers oxygen to tissues throughout the body. Better oxygen delivery means better cellular energy, better repair, and better function across nearly every system.
A Natural Partner to Functional Medicine
Functional medicine has always been about addressing root cause and supporting the body’s ability to clear what’s burdening it through nutrition, lifestyle, supplementation, and time. EBOO is that same philosophy, but more direct. In a controlled session, we can help reduce the pathogen and oxidative load that’s been sitting in your bloodstream, often for years, while supporting the immune and antioxidant systems that should have been clearing it all along.
This is not a replacement for the foundational work. It’s what becomes possible when that foundation is in place and the body needs more focused support to keep moving forward.
EBOO May Support People Experiencing:
Lyme disease and co-infections that have been difficult to fully resolve
What to Expect During EBOO
You’ll be comfortably seated or reclined in a private room with TV and streaming services while we set up IV access in each arm, similar to a blood draw or infusion. Sessions run about an hour to an hour and a half, and our clinical team is with you the entire time, monitoring everything.
At Olos, we plan EBOO sessions with recovery in mind. That often includes IV nutrient and antioxidant support before, during, or after the session, because how your body processes the therapy matters as much as the therapy itself.
Most patients are surprised by how calm the session feels. And what they report afterward is what keeps them coming back.
Ready to talk about EBOO?
If you’ve been dealing with chronic infections, mold illness, or persistent symptoms that haven’t responded to other approaches, EBOO may be worth exploring. We’d love to talk with you about whether it could be a fit and how it would work alongside the rest of your care.
Frequently asked questions
Do I need to be a patient at Olos Medicine to receive EBOO?
Yes. EBOO is a powerful therapy that we use as part of a broader, personalized plan, and we want to know your full health picture before recommending it. Getting started as a patient is straightforward, and our team can guide you through the process.
What conditions can EBOO help with?
EBOO is most commonly used in cases involving chronic infections (including Lyme disease and co-infections), mold and biotoxin illness, chronic viral reactivation, environmental toxicity, autoimmune issues with an infectious or inflammatory driver, and chronic fatigue conditions. Your provider will help determine whether EBOO is appropriate for your specific situation.
How is EBOO different from other ozone therapies?
There are several ways to deliver ozone medically, including major autohemotherapy (MAH), insufflation, and prolozone. EBOO treats a much larger volume of blood than most other ozone methods, uses a closed sterile circuit, and includes both ozone and oxygen exposure in a controlled, measured way. For patients with significant pathogen or toxic burden, EBOO tends to offer more substantial support than smaller-volume ozone therapies.
How is EBOO different from TPE?
Both therapies involve circulating blood outside the body, but they do very different things. TPE removes the plasma (which carries inflammation, toxins, and other unwanted compounds) and replaces it with fresh albumin. EBOO does not remove plasma. Instead, it exposes your blood to ozone and oxygen to support immune function and pathogen clearance, and returns all of your blood components to you. Some patients benefit from both therapies used in sequence. Your provider will help you understand which approach or combination makes sense for you.
Is EBOO safe?
When administered properly by trained clinical staff using medical-grade equipment, EBOO has a well-established safety profile. The circuit is closed and sterile, the ozone concentrations are precisely measured, and you’re monitored throughout the session. As with any therapy involving IV access, there’s a small risk of bruising, soreness, or, very rarely, infection. EBOO is not appropriate for everyone, and we carefully screen each patient before recommending it.
How many sessions will I need?
That depends entirely on what we’re treating and how your body responds. Some patients do well with a short series of three to six sessions. Others, particularly those with more complex chronic infections, may benefit from a longer course. Your provider will recommend a protocol based on your situation and adjust as we go.
Is there downtime?
Most patients return to their normal routine after a session, though we recommend taking it easy that evening and staying well-hydrated. Some patients experience temporary fatigue or flu-like symptoms in the first 24 hours, especially early in the protocol. This is sometimes called a “Herxheimer reaction” and is typically a sign that your body is actively processing pathogen die-off. It usually resolves within a day or two, and your clinical team will walk you through what to watch for and how to support yourself afterward.
Does insurance cover EBOO?
EBOO is considered an integrative therapy and is generally not covered by insurance. Our team can walk you through pricing and package options before you commit to anything.
How do I get started?
Current patients can talk with their provider at their next visit or reach out to the team. New patients can contact us to schedule a consultation and we’ll go from there.